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Cell viability was assessed by calculating the ratio of experimental wells (after subtracting background) to control wells (also after subtracting background)

PAGln induced hypercontractility and altered calcium cycling in isolated cardiomyocytes providing evidence of improper relaxation which corresponds to elevated filling pressures observed in vivo

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At the same time, aging also means declining glutathione synthesis, which offsets the negative impact of reactive oxygen species on the bodys cell health and functions

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BPC-157 and TB-500 operate through distinct but complementary mechanisms